Application of motion analysis in the study of the effect of botulinum toxin to rat vocal folds

Abdul K. Saadah; Nikolas P. Galatsanos; K. Inagi; D. Bless

doi:10.1117/12.274071

9 May 1997 Application of motion analysis in the study of the effect of botulinum toxin to rat vocal folds

Abdul K. Saadah, Nikolas P. Galatsanos, K. Inagi, D. Bless

Author Affiliations +

Proceedings Volume 3033, Medical Imaging 1997: Physiology and Function from Multidimensional Images; (1997) https://doi.org/10.1117/12.274071
Event: Medical Imaging 1997, 1997, Newport Beach, CA, United States

Abstract

In the past we have proposed a system that measures the deformations of the vocal folds from videostroboscopic images of the larynx, in that system: (1) we extract the boundaries of the vocal folds, (2) we register elastically the vocal fold boundaries in successive frames. This yields the displacement vector field (DVF) between adjacent frames, and (3) we fit using a least-squares approach an affine transformation model to succinctly describe the deformations between adjacent frames. In this paper, we present as an example of the capabilities of this system, an initial study of the deformation changes in rat vocal folds pre and post injection with Botulinum toxin. For this application the generated DVF was segmented into right DVF and left DVF and the deformation of each segment is studied separately.

Citation Download Citation

Abdul K. Saadah, Nikolas P. Galatsanos, K. Inagi, and D. Bless "Application of motion analysis in the study of the effect of botulinum toxin to rat vocal folds", Proc. SPIE 3033, Medical Imaging 1997: Physiology and Function from Multidimensional Images, (9 May 1997); https://doi.org/10.1117/12.274071

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