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9 May 1997 Effect of photodynamic therapy in intimal hyperplasia by phthalocyanine conjugated to the scavenger-receptor ligand, maleylated bovine serum albumin
Shigeki Ito, Tsuneyuki Nagae, Shin Ishimaru, Sara Chau, Triet Dang, Leslie Anne Sabiniano, Mizuho Zempo, Mark C. Booth, Lih-Huei L. Liaw, Tatiana B. Krasieva, Bruce J. Tromberg, Johan E. van Lier, Michael W. Berns, Samuel E. Wilson
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Proceedings Volume 3033, Medical Imaging 1997: Physiology and Function from Multidimensional Images; (1997) https://doi.org/10.1117/12.274054
Event: Medical Imaging 1997, 1997, Newport Beach, CA, United States
Abstract
Initial hyperplasia is major cause of restenosis after vascular interventions for arterial occlusive disease. We reported that a fluorescent probe, Texas Red, conjugated to the scavenger-receptor ligand, maleylated bovine serum albumin accumulated almost exclusively in the injured, hyperplastic sites. The purpose of this study is to test the feasibility of enhanced drug delivery to the hyperplastic lesion by targeting the scavenger-receptors.
© (1997) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
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Shigeki Ito, Tsuneyuki Nagae, Shin Ishimaru, Sara Chau, Triet Dang, Leslie Anne Sabiniano, Mizuho Zempo, Mark C. Booth, Lih-Huei L. Liaw, Tatiana B. Krasieva, Bruce J. Tromberg, Johan E. van Lier, Michael W. Berns, and Samuel E. Wilson "Effect of photodynamic therapy in intimal hyperplasia by phthalocyanine conjugated to the scavenger-receptor ligand, maleylated bovine serum albumin", Proc. SPIE 3033, Medical Imaging 1997: Physiology and Function from Multidimensional Images, (9 May 1997); https://doi.org/10.1117/12.274054
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KEYWORDS
Luminescence
Photodynamic therapy
Arteries
Injuries
Surgery
Receptors
Laser therapeutics
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