For active vibration control of buildings in Japan, new system alterative to current active mass dampers are required. Smart structures are candidates for the alternative systems. In order to investigate the possibility, a smart structure was tested for active vibration control of frame structures, in which bending moment of the columns was controlled by magnetostrictive actuators integrated into the columns. The actuators were installed in stages in the bottom part of the column of a H- section. The stages had a different section for effective integration of the actuators into the column, while they had the same bending stiffnesses of the column in the two lateral directions. Excitation tests were carried out for a 3-story building model of a 3.4 m height and a 1600 kg total mass by using a shaking table. In the building model, each column had 2 stages in it's bottom part in the first story, and 4 actuators were installed in each stage of one column. Thus 32 actuators in total were used. The magnetostrictive actuator developed for the building model consisted of a magnetostrictive rod of a 40 mm length and a 20 mm diameter surrounded by a driving coil. The controllers for the building model were designed by the model-matching method and the H(infinity ) control theory to control the 1st-, 2nd-, and 3rd-mode responses, and both controllers were designed so that the system had a 15% damping ratio in all modes. Through the tests, it was shown that the smart structure could effectively reduce the responses of the building model, and the two control strategies had almost the same performance.