Measuring the accuracy and precision of quantitative coronary angiography using a digitally simulated test phantom

Craig A. Morioka; James Stuart Whiting; Michelle T. LeFree

doi:10.1117/12.310855

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24 June 1998 Measuring the accuracy and precision of quantitative coronary angiography using a digitally simulated test phantom

Craig A. Morioka, James Stuart Whiting, Michelle T. LeFree

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Proceedings Volume 3338, Medical Imaging 1998: Image Processing; (1998) https://doi.org/10.1117/12.310855
Event: Medical Imaging '98, 1998, San Diego, CA, United States

Abstract

Quantitative coronary angiography (QCA) diameter measurements have been used as an endpoint measurement in clinical studies involving therapies to reduce coronary atherosclerosis. The accuracy and precision of the QCA measure can affect the sample size and study conclusions of a clinical study. Measurements using x-ray test phantoms can underestimate the precision and accuracy of the actual arteries in clinical digital angiograms because they do not contain complex patient structures. Determining the clinical performance of QCA algorithms under clinical conditions is difficult because: (1) no gold standard test object exists in clinical images, (2) phantom images do not have any structured background noise. We purpose the use of computer simulated arteries as a replacement for traditional angiographic test phantoms to evaluate QCA algorithm performance.

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Craig A. Morioka, James Stuart Whiting, and Michelle T. LeFree "Measuring the accuracy and precision of quantitative coronary angiography using a digitally simulated test phantom", Proc. SPIE 3338, Medical Imaging 1998: Image Processing, (24 June 1998); https://doi.org/10.1117/12.310855

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