Multivariate discriminating algorithm for analyzing laser-induced fluorescence spectra of human gastrointestinal cancer

Wei Chen; Guang Hui Wei

doi:10.1117/12.323509

24 September 1998 Multivariate discriminating algorithm for analyzing laser-induced fluorescence spectra of human gastrointestinal cancer

Wei Chen, Guang Hui Wei

Author Affiliations +

Proceedings Volume 3414, Opto-Contact: Workshop on Technology Transfers, Start-Up Opportunities,and Strategic Alliances; (1998) https://doi.org/10.1117/12.323509
Event: Lasers and Materials in Industry and Opto-Contact Workshop, 1998, Quebec, Canada

Abstract

The purpose of this study has been to evaluate the laser- induced fluorescence characters of normal and malignant stomach tissue in Vitro and in Vivo. The stepwise multivariate discrimination analysis was used to make a multivariate statistical algorithm for analyzing the diagnostic parameters of human stomach tissues fluorescence spectrum. The resulting spectra could be differentiating histologically stomach abnormal tissue from normal tissue with a sensitivity and specificity value of 95% and 97%. The diagnosis results were in excellent agreement with histopathological results.

Citation Download Citation

Wei Chen and Guang Hui Wei "Multivariate discriminating algorithm for analyzing laser-induced fluorescence spectra of human gastrointestinal cancer", Proc. SPIE 3414, Opto-Contact: Workshop on Technology Transfers, Start-Up Opportunities,and Strategic Alliances, (24 September 1998); https://doi.org/10.1117/12.323509

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