Chemo- and biosensor microsystems for clinical applications

Gerald A. Urban; G. Jobst; I. Moser

doi:10.1117/12.333753

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18 December 1998 Chemo- and biosensor microsystems for clinical applications

Gerald A. Urban, G. Jobst, I. Moser

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Proceedings Volume 3539, Chemical Microsensors and Applications; (1998) https://doi.org/10.1117/12.333753
Event: Photonics East (ISAM, VVDC, IEMB), 1998, Boston, MA, United States

Abstract

A miniaturized microanalytical device for the simultaneous monitoring of different metabolites was realized by assembling of a biosensor array produced by thin film technology with a flow-through cell produced by printed circuit board technology. The biosensor array comprises four working electrodes which can be individually configured. Glucose and lactate devices were made for whole blood monitoring. Ex vivo experiments, performed on animals, where the device was continuously operated in an extracorporeal undiluted heparinized blood stream without loss in sensitivity for 48 hours, gave close tracing to routinely used clinical analyzers by using one point in vitro calibration.

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Gerald A. Urban, G. Jobst, and I. Moser "Chemo- and biosensor microsystems for clinical applications", Proc. SPIE 3539, Chemical Microsensors and Applications, (18 December 1998); https://doi.org/10.1117/12.333753

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