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19 January 1999 Depth-resolved tumor phantom detection by second-generation photosensitizers
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Abstract
Determination of the tumor's penetration into the tissue is actual task of optical biopsy. For this aim the depth resolved fluorescence of the second generation sensitizer's molecules has been studied in tissue's phantom at different excitation wavelength. Fluorescence spectra from the superficially and deeply (up to 10 mm) located Chlorin e6 sensitizer's molecules at 355, 532, 660 nm laser excitation were registered. The comparison of the fluorescence signals registered at the different values of penetration into tissues of the probing radiation gives opportunity to define the presence of the sensitizer's molecules in different depth of tissue and to reveal such important clinical parameter as tumor's penetration into depth.
© (1999) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Asatur A. Lalayan and Samvel Harutyunyan "Depth-resolved tumor phantom detection by second-generation photosensitizers", Proc. SPIE 3568, Optical Biopsies and Microscopic Techniques III, (19 January 1999); https://doi.org/10.1117/12.336839
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