Correlation between near-infrared tissue spectra and pH, temperature, and blood flow using partial least squares

Tania Khan; Babs R. Soller; Songbiao Zhang

doi:10.1117/12.351524

9 July 1999 Correlation between near-infrared tissue spectra and pH, temperature, and blood flow using partial least squares

Tania Khan, Babs R. Soller, Songbiao Zhang

Author Affiliations +

Proceedings Volume 3595, Biomedical Diagnostic, Guidance, and Surgical-Assist Systems; (1999) https://doi.org/10.1117/12.351524
Event: BiOS '99 International Biomedical Optics Symposium, 1999, San Jose, CA, United States

Abstract

It has been shown that near-infrared spectroscopy is a feasible technique to non-invasively measure tissue pH in vivo. Since this technique relies on pH-induced changes in heme protein spectra, other factors that affect those spectra were investigated. In this study, the correlation between spectra collected from the bowel (575 - 1100 nm) with local tissue temperature and blood flow were investigated simultaneously with pH changes during eight independent swine hemorrhagic shock experiments.

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Tania Khan, Babs R. Soller, and Songbiao Zhang "Correlation between near-infrared tissue spectra and pH, temperature, and blood flow using partial least squares", Proc. SPIE 3595, Biomedical Diagnostic, Guidance, and Surgical-Assist Systems, (9 July 1999); https://doi.org/10.1117/12.351524

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