High-speed grating-generated electronic coherence microscopy of biological tissue without moving parts

Alexandr Gilerson; Iosif Zeylikovich; Robert R. Alfano

doi:10.1117/12.347501

30 April 1999 High-speed grating-generated electronic coherence microscopy of biological tissue without moving parts

Alexandr Gilerson, Iosif Zeylikovich, Robert R. Alfano

Proceedings Volume 3598, Coherence Domain Optical Methods in Biomedical Science and Clinical Applications III; (1999) https://doi.org/10.1117/12.347501
Event: BiOS '99 International Biomedical Optics Symposium, 1999, San Jose, CA, United States

Abstract

A novel method of high speed grating-generated electronic coherence microscopy is applied to produce depth-lateral images of biological tissue without axial-lateral scanning. Axial-lateral scan is automatically performed by the stationary reflection diffraction grating installed in the Littrow configuration at the reference beam and a cylindrical lens installed in the sample beam. Using several 2D CCD array complex digital imags containing amplitude and phase values the depth-lateral reflections of biological tissue are reconstructed with a simple algorithm. The depth scan of 1.5 mm and the transversal coordinate image about 1.2 mm of the chicken tissue with a depth resolution of 17 micrometers , and a dynamic range about 70 dB are achieved. Final depth-lateral images are similar to OCT images and produced without any moving parts.

Citation Download Citation

Alexandr Gilerson, Iosif Zeylikovich, and Robert R. Alfano "High-speed grating-generated electronic coherence microscopy of biological tissue without moving parts", Proc. SPIE 3598, Coherence Domain Optical Methods in Biomedical Science and Clinical Applications III, (30 April 1999); https://doi.org/10.1117/12.347501

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available