Frequency encoding of source position for multisource reflectance imaging measurements using frequency domain photon migration

Daniel J. Hawrysz; Jeffery S. Reynolds; Eva Marie Sevick-Muraca

doi:10.1117/12.351039

2 July 1999 Frequency encoding of source position for multisource reflectance imaging measurements using frequency domain photon migration

Daniel J. Hawrysz, Jeffery S. Reynolds, Eva Marie Sevick-Muraca

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Proceedings Volume 3600, Biomedical Imaging: Reporters, Dyes, and Instrumentation; (1999) https://doi.org/10.1117/12.351039
Event: BiOS '99 International Biomedical Optics Symposium, 1999, San Jose, CA, United States

Abstract

In order for photon migration imaging to be clinically feasible, data acquisition must be fast and efficient. Rapid data acquisition minimizes error due to patient movement and improves patient acceptance. Multi-pixel imaging techniques offer the fastest method of data acquisition, however difficulties may exist in coupling the data with inversion algorithms. Single pixel measurements, while easier to couple to an inversion algorithm, require longer data acquisition times. Herein a heterodyne procedure for speeding the data acquisition time using single pixel techniques is presented. This simple extension of the heterodyne method enables the use of multiple sources simultaneously with the signal from various source-detector pairs discriminated by FFT analysis.

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Daniel J. Hawrysz, Jeffery S. Reynolds, and Eva Marie Sevick-Muraca "Frequency encoding of source position for multisource reflectance imaging measurements using frequency domain photon migration", Proc. SPIE 3600, Biomedical Imaging: Reporters, Dyes, and Instrumentation, (2 July 1999); https://doi.org/10.1117/12.351039

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KEYWORDS

Modulation

Signal detection

Data acquisition

Heterodyning

Sensors

Semiconductor lasers

Optical fibers

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