Laser desorption mass spectrometry for high-throughput DNA analysis and its applications

C. H. Winston Chen; Valeri V. Golovlev; N. I. Taranenko; S. L. Allman; Narayana R. Isola; N. T. Potter; K. J. Matteson; Linus Y.Y. Chang

doi:10.1117/12.347532

3 May 1999 Laser desorption mass spectrometry for high-throughput DNA analysis and its applications

C. H. Winston Chen, Valeri V. Golovlev, N. I. Taranenko, S. L. Allman, Narayana R. Isola, N. T. Potter, K. J. Matteson, Linus Y.Y. Chang

Author Affiliations +

Proceedings Volume 3602, Advances in Fluorescence Sensing Technology IV; (1999) https://doi.org/10.1117/12.347532
Event: BiOS '99 International Biomedical Optics Symposium, 1999, San Jose, CA, United States

Abstract

Laser desorption mass spectrometry (LDMS) has been developed for DNA sequencing, disease diagnosis, and DNA fingerprinting for forensic applications. With LDMS, the speed of DNA analysis can be much faster than conventional gel electrophoresis. No dye or radioactive tagging to DNA segments for detection is needed. LDMS is emerging as a new alternative technology for DNA analysis.

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C. H. Winston Chen, Valeri V. Golovlev, N. I. Taranenko, S. L. Allman, Narayana R. Isola, N. T. Potter, K. J. Matteson, and Linus Y.Y. Chang "Laser desorption mass spectrometry for high-throughput DNA analysis and its applications", Proc. SPIE 3602, Advances in Fluorescence Sensing Technology IV, (3 May 1999); https://doi.org/10.1117/12.347532

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