New approach for quantitative analysis of myocardial perfusion with magnetic resonance first-pass bolus imaging

Helmut Oswald; Bernd Schnackenburg; Axel Bornstedt; Michael Gross; Nidal Al-Saadi; Eicke Nagel; Eckart Fleck

doi:10.1117/12.349617

20 May 1999 New approach for quantitative analysis of myocardial perfusion with magnetic resonance first-pass bolus imaging

Helmut Oswald, Bernd Schnackenburg, Axel Bornstedt, Michael Gross, Nidal Al-Saadi, Eicke Nagel, Eckart Fleck

Author Affiliations +

Proceedings Volume 3660, Medical Imaging 1999: Physiology and Function from Multidimensional Images; (1999) https://doi.org/10.1117/12.349617
Event: Medical Imaging '99, 1999, San Diego, CA, United States

Abstract

Myocardial perfusion reserve can be noninvasively assessed with cardiovascular magnetic resonance. With magnetic resonance (MR) multislice dynamic imaging techniques it is possible to acquire the complete heart during the first pass of a contrast agent bolus. For diagnostic reasons an important question is to obtain quantitative parameters of the perfusion of the myocardium. We developed a model for the analysis of the contrast agent bolus pass in the myocardium and established a process for the complete task, which will support a routine clinical use delivering these quantitative parameters in a reproducible way. To evaluate the analysis in a collective of patients with single vessel disease and without significant coronary artery disease the signal intensity curves of the first pass of a gadolinium-DTPA bolus injected via a central vein were estimated before and after dipyridamole infusion.

Citation Download Citation

Helmut Oswald, Bernd Schnackenburg, Axel Bornstedt, Michael Gross, Nidal Al-Saadi, Eicke Nagel, and Eckart Fleck "New approach for quantitative analysis of myocardial perfusion with magnetic resonance first-pass bolus imaging", Proc. SPIE 3660, Medical Imaging 1999: Physiology and Function from Multidimensional Images, (20 May 1999); https://doi.org/10.1117/12.349617

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