Human thyroid specimen imaging by fluorescent x-ray computed tomography with synchrotron radiation

Tohoru Takeda; Quanwen Yu; Toru Yashiro; Tetsuya Yuasa; Yasuo Hasegawa; Yuji Itai; Takao Akatsuka

doi:10.1117/12.363728

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22 September 1999 Human thyroid specimen imaging by fluorescent x-ray computed tomography with synchrotron radiation

Tohoru Takeda, Quanwen Yu, Toru Yashiro, Tetsuya Yuasa, Yasuo Hasegawa, Yuji Itai, Takao Akatsuka

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Proceedings Volume 3772, Developments in X-Ray Tomography II; (1999) https://doi.org/10.1117/12.363728
Event: SPIE's International Symposium on Optical Science, Engineering, and Instrumentation, 1999, Denver, CO, United States

Abstract

Fluorescent x-ray computed tomography (FXCT) is being developed to detect non-radioactive contrast materials in living specimens. The FXCT system consists of a silicon (111) channel cut monochromator, an x-ray slit and a collimator for fluorescent x ray detection, a scanning table for the target organ and an x-ray detector for fluorescent x-ray and transmission x-ray. To reduce Compton scattering overlapped on the fluorescent K(alpha) line, incident monochromatic x-ray was set at 37 keV. The FXCT clearly imaged a human thyroid gland and iodine content was estimated quantitatively. In a case of hyperthyroidism, the two-dimensional distribution of iodine content was not uniform, and thyroid cancer had a small amount of iodine. FXCT can be used to detect iodine within thyroid gland quantitatively and to delineate its distribution.

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Tohoru Takeda, Quanwen Yu, Toru Yashiro, Tetsuya Yuasa, Yasuo Hasegawa, Yuji Itai, and Takao Akatsuka "Human thyroid specimen imaging by fluorescent x-ray computed tomography with synchrotron radiation", Proc. SPIE 3772, Developments in X-Ray Tomography II, (22 September 1999); https://doi.org/10.1117/12.363728

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