Paper
18 November 1999 Membrane-based microarrays
Elliott P. Dawson, James Hudson, John Steward, Philip A. Donnell, Wing W. Chan, Richard F. Taylor
Author Affiliations +
Proceedings Volume 3857, Chemical Microsensors and Applications II; (1999) https://doi.org/10.1117/12.370292
Event: Photonics East '99, 1999, Boston, MA, United States
Abstract
Microarrays represent a new approach to the rapid detection and identification of analytes. Studies to date have shown that the immobilization of receptor molecules (such as DNA, oligonucleotides, antibodies, enzymes and binding proteins) onto silicon and polymeric substrates can result in arrays able to detect hundreds of analytes in a single step. The formation of the receptor/analyte complex can, itself, lead to detection, or the complex can be interrogated through the use of fluorescent, chemiluminescent or radioactive probes and ligands.
© (1999) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Elliott P. Dawson, James Hudson, John Steward, Philip A. Donnell, Wing W. Chan, and Richard F. Taylor "Membrane-based microarrays", Proc. SPIE 3857, Chemical Microsensors and Applications II, (18 November 1999); https://doi.org/10.1117/12.370292
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KEYWORDS
Receptors

Polymers

Molecules

Biological research

Composites

Genetics

Silicon

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