Laser-induced thermotherapy of renal cell carcinoma in man: dosimetry, ultrasound, and histopathologic correlation

J. Chandler Williams M.D.; Peter N. Swischuk; Patricia M. Morrison; Joseph Chiao

doi:10.1117/12.386259

17 May 2000 Laser-induced thermotherapy of renal cell carcinoma in man: dosimetry, ultrasound, and histopathologic correlation

J. Chandler Williams M.D., Peter N. Swischuk, Patricia M. Morrison, Joseph Chiao

Author Affiliations +

Proceedings Volume 3907, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems X; (2000) https://doi.org/10.1117/12.386259
Event: BiOS 2000 The International Symposium on Biomedical Optics, 2000, San Jose, CA, United States

Abstract

Laser-induced thermoterapy (LITT), is the interstitial application of laser energy to achieve tissue coagulation by a thermal process. This is achieved by implanting the laser delivery fiber directly into the target tissue and firing the laser. LITT is being investigated and evaluated clinically as a treatment for renal tumors. The objective of this study was to determine if ultrasound could be used as a real-time monitoring modality of LITT during the coagulation process. Ultrasound characterization was correlated with histopathologic changes and dosimetry. In addition, temperature was monitored and correlated as well.

Citation Download Citation

J. Chandler Williams M.D., Peter N. Swischuk, Patricia M. Morrison, and Joseph Chiao "Laser-induced thermotherapy of renal cell carcinoma in man: dosimetry, ultrasound, and histopathologic correlation", Proc. SPIE 3907, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems X, (17 May 2000); https://doi.org/10.1117/12.386259

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