3D image reconstruction algorithms for cryo-electron-microscopy images of virus particles

Peter C. Doerschuk; John E. Johnson

doi:10.1117/12.409274

16 November 2000 3D image reconstruction algorithms for cryo-electron-microscopy images of virus particles

Peter C. Doerschuk, John E. Johnson

Proceedings Volume 4123, Image Reconstruction from Incomplete Data; (2000) https://doi.org/10.1117/12.409274
Event: International Symposium on Optical Science and Technology, 2000, San Diego, CA, United States

Abstract

A statistical model for the object and the complete image formation process in cryo electron microscopy of viruses is presented. Using this model, maximum likelihood reconstructions of the 3D structure of viruses are computed using the expectation maximization algorithm and an example based on Cowpea mosaic virus is provided.

Citation Download Citation

Peter C. Doerschuk and John E. Johnson "3D image reconstruction algorithms for cryo-electron-microscopy images of virus particles", Proc. SPIE 4123, Image Reconstruction from Incomplete Data, (16 November 2000); https://doi.org/10.1117/12.409274

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