Detection of human colonic adenoma by laser-induced autofluorescence integrated with diffuse reflectance spectroscopy

Guilin Tang; Haibao Lu; Yangde Zhang; Shuhua Yan; Zhifeng Chen

doi:10.1117/12.403968

11 October 2000 Detection of human colonic adenoma by laser-induced autofluorescence integrated with diffuse reflectance spectroscopy

Guilin Tang, Haibao Lu, Yangde Zhang, Shuhua Yan, Zhifeng Chen

Author Affiliations +

Proceedings Volume 4224, Biomedical Photonics and Optoelectronic Imaging; (2000) https://doi.org/10.1117/12.403968
Event: Optics and Optoelectronic Inspection and Control: Techniques, Applications, and Instruments, 2000, Beijing, China

Abstract

A combined in vivo measurement system integrating laser- induced autofluorescence (LIAF) and diffuse reflectance spectroscopy (DRS) measurement was developed and investigated for detecting colonic adenoma. The system could work with regular endoscopy examination. A three- layer backpropagating neural network (BNN) was built to differentiate the two tissue classes. The preliminary results gave the mean predictive accuracy, sensitivity and specificity better than either of the two methods used alone.

Citation Download Citation

Guilin Tang, Haibao Lu, Yangde Zhang, Shuhua Yan, and Zhifeng Chen "Detection of human colonic adenoma by laser-induced autofluorescence integrated with diffuse reflectance spectroscopy", Proc. SPIE 4224, Biomedical Photonics and Optoelectronic Imaging, (11 October 2000); https://doi.org/10.1117/12.403968

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