Diffuse and localized reflectance measurements of hemoglobin and hematocrit in human skin

Omar S. Khalil; Xiaomao Wu; Shu-Jen Yeh; Tzyy-Wen Jeng

doi:10.1117/12.431522

4 May 2001 Diffuse and localized reflectance measurements of hemoglobin and hematocrit in human skin

Omar S. Khalil, Xiaomao Wu, Shu-Jen Yeh, Tzyy-Wen Jeng

Proceedings Volume 4241, Saratov Fall Meeting 2000: Optical Technologies in Biophysics and Medicine II; (2001) https://doi.org/10.1117/12.431522
Event: Saratov Fall Meeting 2000, 2001, Saratov, Russian Federation

Abstract

We conducted visible/near infrared optical measurements on the forearm of human subjects using a commercial diffuse reflectance spectrophotometer, and a breadboard temperature- controlled localized reflectance tissue photometer. Calibration relationships were established between skin reflectance signal and reference blood hemoglobin (Hb) concentration, or hematocrit values (Hct). These were then used to predict Hb and Hct values from optical measurement in a cross validation analysis. Different linear least- squares models for the prediction of Hb and Hct are presented and shows the ability to predict both. It was possible to screen prospective blood donors with low Hb concentration. It was possible to predict anemic subjects in the limited prospective blood donor population.

Citation Download Citation

Omar S. Khalil, Xiaomao Wu, Shu-Jen Yeh, and Tzyy-Wen Jeng "Diffuse and localized reflectance measurements of hemoglobin and hematocrit in human skin", Proc. SPIE 4241, Saratov Fall Meeting 2000: Optical Technologies in Biophysics and Medicine II, (4 May 2001); https://doi.org/10.1117/12.431522

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