High-resolution optical tomographic imaging of soft biological tissues

Ruikang K. Wang; James B. Elder

doi:10.1117/12.431514

4 May 2001 High-resolution optical tomographic imaging of soft biological tissues

Ruikang K. Wang, James B. Elder

Proceedings Volume 4241, Saratov Fall Meeting 2000: Optical Technologies in Biophysics and Medicine II; (2001) https://doi.org/10.1117/12.431514
Event: Saratov Fall Meeting 2000, 2001, Saratov, Russian Federation

Abstract

Optical Coherence tomography is a recently developed imaging technique that has potential to improve the diagnostic limits of the currently available imaging techniques, allowing wide range of clinical disorders to be addressed at an early stage. We report in this paper the application of our OCT system to image soft biological tissues with resolution approaching 9 microns. The tissue targets include biological species, the rat and human G.I. tract tissues. For the G.I. tract tissues, both the normal and pathological specimens, including oesophagus, stomach and colon were imaged. Sharp differentiation of structures and features was observed. The images acquired in this study provide information on tissue microstructure that could only previously be obtained with conventional excisional biopsy.

Citation Download Citation

Ruikang K. Wang and James B. Elder "High-resolution optical tomographic imaging of soft biological tissues", Proc. SPIE 4241, Saratov Fall Meeting 2000: Optical Technologies in Biophysics and Medicine II, (4 May 2001); https://doi.org/10.1117/12.431514

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available