Use of a fast gated CCD camera for imaging through turbid media

Gianluca Valentini; Cosimo D'Andrea; Daniela Comelli; Rinaldo Cubeddu

doi:10.1117/12.434490

29 June 2001 Use of a fast gated CCD camera for imaging through turbid media

Gianluca Valentini, Cosimo D'Andrea, Daniela Comelli, Rinaldo Cubeddu

Proceedings Volume 4250, Optical Tomography and Spectroscopy of Tissue IV; (2001) https://doi.org/10.1117/12.434490
Event: BiOS 2001 The International Symposium on Biomedical Optics, 2001, San Jose, CA, United States

Abstract

In this paper we present a system for optical imaging in turbid media based on an intensified CCD camera. The time-gating capability of the light intensifier has been used to acquire time sliced images of the light transmitted through phantoms made of intralipid and ink solutions. Then, we analyzed the images by fitting the time series with a theoretical expression for photon migration. This allowed us to recover the maps of the absorption ((mu) _a) and scattering ((mu) _s') coefficients in an extended area of the samples. Using our system a possible heterogeneity in the sample can be easily detected. We characterized the performances of the system following two approaches. First, we evaluated the linearity of the relationship between the recovered absorption coefficient and the ink concentration and between the recovered scattering coefficient and the intralipid content (homogeneous samples). Then, we measured the apparent contrast in the (mu) _s' maps resulting from small inclusions with a scattering coefficient higher and lower with respect to a homogeneous background (heterogeneous samples). Results encourage further researches.

Citation Download Citation

Gianluca Valentini, Cosimo D'Andrea, Daniela Comelli, and Rinaldo Cubeddu "Use of a fast gated CCD camera for imaging through turbid media", Proc. SPIE 4250, Optical Tomography and Spectroscopy of Tissue IV, (29 June 2001); https://doi.org/10.1117/12.434490

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available