Blood oxygenation measurements with optical coherence tomography

Dirk J. Faber; Egbert G. Mik; Maurice C.G. Aalders; Freek J. van der Meer; Ton G. J. M. van Leeuwen

doi:10.1117/12.427883

23 May 2001 Blood oxygenation measurements with optical coherence tomography

Dirk J. Faber, Egbert G. Mik, Maurice C.G. Aalders, Freek J. van der Meer, Ton G. J. M. van Leeuwen

Proceedings Volume 4251, Coherence Domain Optical Methods in Biomedical Science and Clinical Applications V; (2001) https://doi.org/10.1117/12.427883
Event: BiOS 2001 The International Symposium on Biomedical Optics, 2001, San Jose, CA, United States

Abstract

The feasibility of Optical Coherence Tomography to determine the oxygenation of whole blood was investigated on porcine blood samples. Our experimental data show a sensitivity in the OCT spectral content to changes in oxygenation that qualitatively correspond to expectations based on the absorption spectra of oxidized and reduced hemoglobin, using a broadband source operating at the isobestic wavelength of 800 nm.

Citation Download Citation

Dirk J. Faber, Egbert G. Mik, Maurice C.G. Aalders, Freek J. van der Meer, and Ton G. J. M. van Leeuwen "Blood oxygenation measurements with optical coherence tomography", Proc. SPIE 4251, Coherence Domain Optical Methods in Biomedical Science and Clinical Applications V, (23 May 2001); https://doi.org/10.1117/12.427883

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