Simple optical computing device for chemical analysis

Olusola O. Soyemi; Lixia Zhang; DeLyle Eastwood; Hongli Li; Paul J. Gemperline; Michael L. Myrick

doi:10.1117/12.426870

15 May 2001 Simple optical computing device for chemical analysis

Olusola O. Soyemi, Lixia Zhang, DeLyle Eastwood, Hongli Li, Paul J. Gemperline, Michael L. Myrick

Proceedings Volume 4284, Functional Integration of Opto-Electro-Mechanical Devices and Systems; (2001) https://doi.org/10.1117/12.426870
Event: Symposium on Integrated Optics, 2001, San Jose, CA, United States

Abstract

Multivariate Optical Computing (MOC) devices have the potential of greatly simplifying as well as reducing the cost of applying the mathematics of multivariate regression to problems of chemical analysis in the real world. These devices utilize special optical interference coatings known as multivariate optical elements (MOEs) that are encoded with pre-determined spectroscopic patterns to selectively quantify a chemical species of interest in the presence of other interfering species. A T-format prototype of the first optical computing device is presented utilizing a multilayer MOE consisting of alternating layers of two metal oxide films (Nb₂O₅ and SiO₂) on a BK-7 glass substrate. The device was tested by using it to quantify copper uroporphyrin in a quaternary mixture consisting of uroporphyrin (freebase), tin uroporphyrin, nickel uroporphyrin, and copper uroporphyrin. A standard error of prediction (SEP) of 0.86(mu) M was obtained for copper uroporphyrin.

Citation Download Citation

Olusola O. Soyemi, Lixia Zhang, DeLyle Eastwood, Hongli Li, Paul J. Gemperline, and Michael L. Myrick "Simple optical computing device for chemical analysis", Proc. SPIE 4284, Functional Integration of Opto-Electro-Mechanical Devices and Systems, (15 May 2001); https://doi.org/10.1117/12.426870

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