Reference-compensated surface plasmon resonance biosensor for detection of foodborne pathogens

Jiri Homola; Jakub Dostalek; Shengfu Chen; Avraham Rasooly; Shaoyi Jiang; Sinclair S. Yee

doi:10.1117/12.427068

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8 May 2001 Reference-compensated surface plasmon resonance biosensor for detection of foodborne pathogens

Jiri Homola, Jakub Dostalek, Shengfu Chen, Avraham Rasooly, Shaoyi Jiang, Sinclair S. Yee

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Proceedings Volume 4416, Optical Engineering for Sensing and Nanotechnology (ICOSN 2001); (2001) https://doi.org/10.1117/12.427068
Event: Optical Engineering for Sensing and Nanotechnology (ICOSN '01), 2001, Yokohama, Japan

Abstract

We present a dual-channel surface plasmon resonance (SPR) biosensor and demonstrate its applicability to detection of foodborne pathogens such as Staphylococcal enterotoxin B (SEB). Experimental results indicate that the SPR biosensor can detect SEB at very low concentrations: 5 ng/ml in pure samples directly, 0.5 ng/ml in both pure samples and in milk using a sandwich assay.

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Jiri Homola, Jakub Dostalek, Shengfu Chen, Avraham Rasooly, Shaoyi Jiang, and Sinclair S. Yee "Reference-compensated surface plasmon resonance biosensor for detection of foodborne pathogens", Proc. SPIE 4416, Optical Engineering for Sensing and Nanotechnology (ICOSN 2001), (8 May 2001); https://doi.org/10.1117/12.427068

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