Porphyrins for photodynamic therapy of cancer

Rodica-Mariana Ion; Mihail-Lucian Pascu

doi:10.1117/12.432903

29 June 2001 Porphyrins for photodynamic therapy of cancer

Rodica-Mariana Ion, Mihail-Lucian Pascu

Proceedings Volume 4430, ROMOPTO 2000: Sixth Conference on Optics; (2001) https://doi.org/10.1117/12.432903
Event: ROMOPTO 2000: Sixth Conference on Optics, 2000, Bucharest, Romania

Abstract

Photodynamic therapy (PDT) of cancer is based on the dye- sensitized photooxidation of different biological targets in the tumoral tissue yielding to a photochemically induced cell's death. The effectiveness of this treatment method depends on the photophysical and photochemical properties of the used photosensitizer-drug during the irradiation with visible light (laser beam) and/or the ionizing radiation. The purpose of this paper is to summarize the photodynamic therapy applications: substitution effects, ionization and aggregation processes effects, photodegradation reaction implications, the correlation with some medical applications on human brain cells.

Citation Download Citation

Rodica-Mariana Ion and Mihail-Lucian Pascu "Porphyrins for photodynamic therapy of cancer", Proc. SPIE 4430, ROMOPTO 2000: Sixth Conference on Optics, (29 June 2001); https://doi.org/10.1117/12.432903

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