New generation of integrated probes for laser Doppler perfusion monitoring: construction and in-vivo results

Alexander N. Serov; Sjoerd Oosterbaan; Janharm Nieland; Herma van Kranenburg; R. Verboom; Herman H. P. Th. Bekman; Frits F. M. de Mul; Wiendelt Steenbergen

doi:10.1117/12.466644

13 May 2002 New generation of integrated probes for laser Doppler perfusion monitoring: construction and in-vivo results

Alexander N. Serov, Sjoerd Oosterbaan, Janharm Nieland, Herma van Kranenburg, R. Verboom, Herman H. P. Th. Bekman, Frits F. M. de Mul, Wiendelt Steenbergen

Author Affiliations +

Proceedings Volume 4615, Biomedical Diagnostic, Guidance, and Surgical-Assist Systems IV; (2002) https://doi.org/10.1117/12.466644
Event: International Symposium on Biomedical Optics, 2002, San Jose, CA, United States

Abstract

Integrated probes have been developed containing the essential optoelectronic components necessary for monitoring tissue perfusion using the laser Doppler principle. The device contains a VCSEL for illumination, and a chip with photodetectors, amplifiers for signal enhancement, and digital circuitry for external probe control. VCSEL and detector chip are mounted on a common ceramic platform. A Peltier element may be included for temperature stabilisation, or thermal cycling for physiological purposes. Two special chips have been developed: one containing an array of five detectors, at various distances from the laser, which will allow for some degree of depth discrimination, and a single detector chip. In this paper the probe designs are presented and some results of in vivo measurements are shown.

Citation Download Citation

Alexander N. Serov, Sjoerd Oosterbaan, Janharm Nieland, Herma van Kranenburg, R. Verboom, Herman H. P. Th. Bekman, Frits F. M. de Mul, and Wiendelt Steenbergen "New generation of integrated probes for laser Doppler perfusion monitoring: construction and in-vivo results", Proc. SPIE 4615, Biomedical Diagnostic, Guidance, and Surgical-Assist Systems IV, (13 May 2002); https://doi.org/10.1117/12.466644

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available