Novel modeling techniques for tumor diagnostics using pulsed laser sources

Mohamed Sakami; Kunal Mitra; Tuan Vo-Dinh

doi:10.1117/12.466643

13 May 2002 Novel modeling techniques for tumor diagnostics using pulsed laser sources

Mohamed Sakami, Kunal Mitra, Tuan Vo-Dinh

Proceedings Volume 4615, Biomedical Diagnostic, Guidance, and Surgical-Assist Systems IV; (2002) https://doi.org/10.1117/12.466643
Event: International Symposium on Biomedical Optics, 2002, San Jose, CA, United States

Abstract

In this paper, a two-dimensional transient radiation transport algorithm is developed to analyze short pulse laser transport through a tissue medium having tumors and inhomogeneities imbedded in it. Short pulse probing techniques have distinct advantages over conventional very large pulse width or cw lasers primarily due to the additional information conveyed about the tissue interior by the temporal variation of the observed signal. The distinct feature is the multiple scattering induced temporal signatures that persists for time periods greater than the duration of the source pulse and is a function of the source pulse width, the scattering/absorbing properties and nature of the medium, the location in the medium where the properties undergo changes. A wide range of parameters such as tissue and tumor size, scattering/absorbing properties and phase function of tissues and tumors, tumor location, laser beam diameter will affect the temporal and spatial distribution of the reflected and transmitted optical signals. The goal is to perform a parametric study in order to gain insight about laser-tissue interaction characteristics with the goal to detect tumors.

Citation Download Citation

Mohamed Sakami, Kunal Mitra, and Tuan Vo-Dinh "Novel modeling techniques for tumor diagnostics using pulsed laser sources", Proc. SPIE 4615, Biomedical Diagnostic, Guidance, and Surgical-Assist Systems IV, (13 May 2002); https://doi.org/10.1117/12.466643

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