Interferometric sensors based on surface plasmon resonance

Chien-ming Wu; Shen-Fen Joe; Liann-Be Chang

doi:10.1117/12.463797

26 March 2002 Interferometric sensors based on surface plasmon resonance

Chien-ming Wu, Shen-Fen Joe, Liann-Be Chang

Proceedings Volume 4616, Optical Fibers and Sensors for Medical Applications II; (2002) https://doi.org/10.1117/12.463797
Event: International Symposium on Biomedical Optics, 2002, San Jose, CA, United States

Abstract

A common-path, heterodyne interferometric system for studying the phase variations under surface plasmon resonance (SPR) is presented. The reflected beam from SPR is further going into a total internal reflection device (TIR) for increasing the sensitivity by the phase shift between TE-wave and TM-wave, as described by the Fresneli's equation. With the combination of a SPR prism and a TIR prism, the system can avoid the change of direction in the output light, which is always happened when only a SPR prism has been used. An unaltered output light is convenient for the detection devices. The system utilizes a pair of orthogonally linearly polarized beams with heterodyne frequency of 60 kHz as the light source. They are perfectly collinear so that the noises resulting from the ambient conditions are greatly reduced. Compared with the technique of reflectivity variation measurement, which is widely used in traditional SPR, the phase variation measurement using common-path, heterodyne techniques is estimated to be higher in sensitivity and thus can be used as a high-sensitivity-demanded biosensor.

Citation Download Citation

Chien-ming Wu, Shen-Fen Joe, and Liann-Be Chang "Interferometric sensors based on surface plasmon resonance", Proc. SPIE 4616, Optical Fibers and Sensors for Medical Applications II, (26 March 2002); https://doi.org/10.1117/12.463797

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available