Drug effects on functional structures in isolated perfused pig heart

Tobias Trinks; Robert Rauh M.D.; Michael Hiller; Manfred D. Kessler

doi:10.1117/12.469453

5 June 2002 Drug effects on functional structures in isolated perfused pig heart

Tobias Trinks, Robert Rauh M.D., Michael Hiller, Manfred D. Kessler

Proceedings Volume 4623, Functional Monitoring and Drug-Tissue Interaction; (2002) https://doi.org/10.1117/12.469453
Event: International Symposium on Biomedical Optics, 2002, San Jose, CA, United States

Abstract

Until today monitoring of immediate drug tissue interaction in living organs is an unsolved problem. However, for the development of new drugs and the improvement of medical therapy outcome it would be helpful to get new tools to visualize drug effects on tissue directly. With the EMPHO II SSK and a 3D-scanning device we detected changes of functional structures in an isolated perfused pig heart model after adding commonly used drugs like verapamil, nitroglycerin and salviae miltiorrhizae (Chinese herbal drug). In the paper the results are presented.

Citation Download Citation

Tobias Trinks, Robert Rauh M.D., Michael Hiller, and Manfred D. Kessler "Drug effects on functional structures in isolated perfused pig heart", Proc. SPIE 4623, Functional Monitoring and Drug-Tissue Interaction, (5 June 2002); https://doi.org/10.1117/12.469453

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