Wavelength ratiometric fluorescent probes for glucose

Nicholas DiCesare; Joseph R. Lakowicz

doi:10.1117/12.469790

4 June 2002 Wavelength ratiometric fluorescent probes for glucose

Proceedings Volume 4625, Clinical Diagnostic Systems: Technologies and Instrumentation; (2002) https://doi.org/10.1117/12.469790
Event: International Symposium on Biomedical Optics, 2002, San Jose, CA, United States

Abstract

We have developed a new series of glucose sensitive fluorophores that display shifts in emission wavelengths upon the binding of glucose. Complexation of glucose with the boronic acid moiety changes both its orbital hybridization and its ability to accept and donate electrons. This change results in distinct emission spectra for the fluorophores when free in solution or complexed with glucose.

Citation Download Citation

Nicholas DiCesare and Joseph R. Lakowicz "Wavelength ratiometric fluorescent probes for glucose", Proc. SPIE 4625, Clinical Diagnostic Systems: Technologies and Instrumentation, (4 June 2002); https://doi.org/10.1117/12.469790

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