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24 April 2002 Effect of knowledge-guided colon segmentation in automated detection of polyps in CT colonography
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We developed a novel automated technique for segmenting the colonic wall in computer-aided detection of polyps in CT colonography. The technique is designed to minimize the presence of extracolonic components, such as small bowel, in the segmented colon. The colon segmentations were evaluated subjectively by four radiologists. On average, 98% of the visible colonic wall was covered by the segmentation. The amount of extracolonic components was reduced by 50% compared with our previously used anatomy-oriented colon segmentation technique, but approximately 10-15% of the segmentation still contained extracolonic components. When the technique was used with our fully automated computer-aided polyp detection scheme at a 100% by-patient detection sensitivity, the false-positive rate was reduced by 20% from 2.5 false positives to 2.0 false positives per patient. These preliminary results suggest that our new colon segmentation technique can improve the specificity of our CAD scheme significantly without degradation in the detection sensitivity.
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Janne J. Nappi, Abraham H. Dachman, Peter MacEneaney, and Hiroyuki Yoshida "Effect of knowledge-guided colon segmentation in automated detection of polyps in CT colonography", Proc. SPIE 4683, Medical Imaging 2002: Physiology and Function from Multidimensional Images, (24 April 2002);

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