Two-modality gamma detection of blood volume by camera imaging and nonimaging stethoscope for kinetic studies of cardiovascular control in nuclear medicine

Bernard Eclancher; Jacques Chambron; Barbu Dumitresco; Miklos Karman; Agnes Pszota; Atilla Simon; Anna Didon-Poncelet; Jean Demangeat

doi:10.1117/12.463621

24 April 2002 Two-modality γ detection of blood volume by camera imaging and nonimaging stethoscope for kinetic studies of cardiovascular control in nuclear medicine

Bernard Eclancher, Jacques Chambron, Barbu Dumitresco, Miklos Karman, Agnes Pszota, Atilla Simon, Anna Didon-Poncelet, Jean Demangeat

Author Affiliations +

Proceedings Volume 4683, Medical Imaging 2002: Physiology and Function from Multidimensional Images; (2002) https://doi.org/10.1117/12.463621
Event: Medical Imaging 2002, 2002, San Diego, California, United States

Abstract

The quantification of rapid hemodynamic reactions to wide and slow breathing movements has been performed, by two modalities (gamma) -left ventriculography of ^99mTc-labeled blood volume, in anterior oblique incidence on standing and even exercising healthy volunteers and cardiac patients. A highly sensitive stethoscope delivered whole (gamma) -counts acquired at 30 msec intervals in a square field of view including the left ventricle, in a one dimensional low resolution imaging mode for beat to beat analysis. A planar 2D (gamma) -camera imaging of the same cardiac area was then performed without cardiac gating for alternate acquisitions during deep inspiration and deep expiration, completed by a 3D MRI assessment of the stethoscope detection field. Young healthy volunteers displayed wide variations of diastolic times and stroke volumes, as a result of enhanced baroreflex control, together with +/- 16% variations of the stethoscope's background blood volume counts. Any of the components of these responses were shifted, abolished or even inverted as a result of either obesity, hypertension, aging or cardiac pathologies. The assessment of breathing control of the cardiovascular system by the beat to beat (gamma) -ventriculography combined with nuclear 2D and 3D MRI imaging is a kinetic method allowing the detection of functional anomalies in still ambulatory patients.

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Bernard Eclancher, Jacques Chambron, Barbu Dumitresco, Miklos Karman, Agnes Pszota, Atilla Simon, Anna Didon-Poncelet, and Jean Demangeat "Two-modality γ detection of blood volume by camera imaging and nonimaging stethoscope for kinetic studies of cardiovascular control in nuclear medicine", Proc. SPIE 4683, Medical Imaging 2002: Physiology and Function from Multidimensional Images, (24 April 2002); https://doi.org/10.1117/12.463621

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KEYWORDS

Blood

Chest

Heart

Cameras

Magnetic resonance imaging

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Electrocardiography

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