EM-IntraSPECT algorithm with ordered subsets (OSEMIS) for nonuniform attenuation correction in cardiac imaging

Andrzej Krol; Ifeanyi Echeruo; Roberto B. Solgado; Amol S. Hardikar; James E. Bowsher; David H. Feiglin; Frank Deaver Thomas; Edward Lipson; Ioana L. Coman

doi:10.1117/12.467057

9 May 2002 EM-IntraSPECT algorithm with ordered subsets (OSEMIS) for nonuniform attenuation correction in cardiac imaging

Andrzej Krol, Ifeanyi Echeruo, Roberto B. Solgado, Amol S. Hardikar, James E. Bowsher, David H. Feiglin, Frank Deaver Thomas, Edward Lipson, Ioana L. Coman

Author Affiliations +

Proceedings Volume 4684, Medical Imaging 2002: Image Processing; (2002) https://doi.org/10.1117/12.467057
Event: Medical Imaging 2002, 2002, San Diego, California, United States

Abstract

Performance of the EM-IntraSPECT (EMIS) algorithm with ordered subsets (OSEMIS) for non-uniform attenuation correction in the chest was assessed. EMIS is a maximum- likelihood expectation maximization(MLEM) algorithm for simultaneously estimating SPECT emission and attenuation parameters from emission data alone. EMIS uses the activity within the patient as transmission tomography sources, with which attenuation coefficients can be estimated. However, the reconstruction time is long. The new algorithm, OSEMIS, is a modified EMIS algorithm based on ordered subsets. Emission Tc-99m SPECT data were acquired over 360 degree(s) in non-circular orbit from a physical chest phantom using clinical protocol. Both a normal and a defect heart were considered. OSEMIS was evaluated in comparison to EMIS and a conventional MLEM with a fixed uniform attenuation map. Wide ranges of image measures were evaluated, including noise, log-likelihood, and region quantification. Uniformity was assessed from bull's eye plots of the reconstructed images. For the appropriate subset size, OSEMIS yielded essentially the same images as EMIS and better than MLEM, but required only one-tenth as many iterations. Consequently, adequate images were available in about fifteen iterations.

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Andrzej Krol, Ifeanyi Echeruo, Roberto B. Solgado, Amol S. Hardikar, James E. Bowsher, David H. Feiglin, Frank Deaver Thomas, Edward Lipson, and Ioana L. Coman "EM-IntraSPECT algorithm with ordered subsets (OSEMIS) for nonuniform attenuation correction in cardiac imaging", Proc. SPIE 4684, Medical Imaging 2002: Image Processing, (9 May 2002); https://doi.org/10.1117/12.467057

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