Synthesis and surface modification of superparamagnetic nanoparticles for biomedical applications

Nathan Kohler; Yong Zhang; Brad Busche; Miqin Zhang

doi:10.1117/12.453767

4 October 2002 Synthesis and surface modification of superparamagnetic nanoparticles for biomedical applications

Nathan Kohler, Yong Zhang, Brad Busche, Miqin Zhang

Proceedings Volume 4810, Properties of Metal Nanostructures; (2002) https://doi.org/10.1117/12.453767
Event: International Symposium on Optical Science and Technology, 2002, Seattle, WA, United States

Abstract

Monodispersed superparamagnetic nanoparticles were synthesized from aqueous iron chloride solutions and were modified with poly(ethylene glycol) self assembled monolayers to improve their dispersion, biocompatibility and intracellular uptake for biomedical applications. Transmission electron micrographs (TEM) and atomic force microscopy (AFM) showed an average particle size of 10-30 nm and confirmed particle dispersion following surface modification with PEG. Fourier transform infrared spectroscopy (FTIR) confirmed the presence of PEG on the nanoparticle surface and the particles were further characterized with electron energy loss spectroscopy (EELS).

Citation Download Citation

Nathan Kohler, Yong Zhang, Brad Busche, and Miqin Zhang "Synthesis and surface modification of superparamagnetic nanoparticles for biomedical applications", Proc. SPIE 4810, Properties of Metal Nanostructures, (4 October 2002); https://doi.org/10.1117/12.453767

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available