Construction of tissue autofluorescence spectra by Monte-Carlo simulation

Xiaodong Chen; Hongbo Xie; Zhi Xu; Daoyin Yu

doi:10.1117/12.483003

12 September 2002 Construction of tissue autofluorescence spectra by Monte-Carlo simulation

Xiaodong Chen, Hongbo Xie, Zhi Xu, Daoyin Yu

Proceedings Volume 4916, Optics in Health Care and Biomedical Optics: Diagnostics and Treatment; (2002) https://doi.org/10.1117/12.483003
Event: Photonics Asia, 2002, Shanghai, China

Abstract

This study investigated a bilayer gastrointestinal normal tissue (including mucosa and submucosa layers) and a cancerous tissue model (including adenoma and submucosa layers), and reconstructed their Laser-Induced Autofluorescence (LIAF) spectra by Monte-Carlo simulation. The good correlation between the reconstructed spectra and experimental spectra suggested that Monte-Carlo simulation can accurately describe the generation and transportation of fluorescence in tissue and therefore can detect cancerous tissue by revealing the real biophysical and biochemical information of tissue.

Citation Download Citation

Xiaodong Chen, Hongbo Xie, Zhi Xu, and Daoyin Yu "Construction of tissue autofluorescence spectra by Monte-Carlo simulation", Proc. SPIE 4916, Optics in Health Care and Biomedical Optics: Diagnostics and Treatment, (12 September 2002); https://doi.org/10.1117/12.483003

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