The Photonsensitized Mechanism Of Hematoporphyrin Derivatives (MPD) In Cancer Therapy

S. H. Liu; L. K. Hui; J. R. Zhang; J. H. Chen; W. Zhang; Y. M. Ding; S. P. Jiang; S. H. Lian; H. G. Shen

doi:10.1117/12.943768

27 March 1985 The Photonsensitized Mechanism Of Hematoporphyrin Derivatives (MPD) In Cancer Therapy

S. H. Liu, L. K. Hui, J. R. Zhang, J. H. Chen, W. Zhang, Y. M. Ding, S. P. Jiang, S. H. Lian, H. G. Shen

Proceedings Volume 0492, 1984 European Conf on Optics, Optical Systems, and Applications; (1985) https://doi.org/10.1117/12.943768
Event: 1984 European Conference on Optics, Optical Systems and Applications, 1984, Amsterdam, Netherlands

Abstract

This paper reports on experimental results of the photosensitized mechanism of HPD in cancer therapy. Human stomach cancer cells and Hela cells were chosen as the object of study. Two kinds of HPD were used being irradiated by either pulsed or CW laser light. The results showed that the main mechanism in photosensitized cancer therapy was singlet oxygen. The energy levels of HPD and HP were calculated and the photodynamic reaction process as well as it's corresponding physical model were discussed.

Citation Download Citation

S. H. Liu, L. K. Hui, J. R. Zhang, J. H. Chen, W. Zhang, Y. M. Ding, S. P. Jiang, S. H. Lian, and H. G. Shen "The Photonsensitized Mechanism Of Hematoporphyrin Derivatives (MPD) In Cancer Therapy", Proc. SPIE 0492, 1984 European Conf on Optics, Optical Systems, and Applications, (27 March 1985); https://doi.org/10.1117/12.943768

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