Optical spectroscopy diagnosis for serum of normal and digestive canal cancer

Xiaozhou Li; Huiqiang Jin; Yuepeng Wang

doi:10.1117/12.516956

1 August 2003 Optical spectroscopy diagnosis for serum of normal and digestive canal cancer

Xiaozhou Li, Huiqiang Jin, Yuepeng Wang

Proceedings Volume 4948, 25th International Congress on High-Speed Photography and Photonics; (2003) https://doi.org/10.1117/12.516956
Event: 25th international Congress on High-Speed photography and Photonics, 2002, Beaune, France

Abstract

To investigate the spectral specialities of digestive cancer serum for diagnosis, fluorescence and Raman spectra of normal, digestive cancer (both before and after operation), such as stomach cancer, esophagus cancer and atrophic gastritis sera were measured in the visible region in this study. Results demonstrate several points. First, all spectra except esophagus cancer were characterized by three sharp peaks (A, B and C), but we cannot differentiate them from each other at once. The intensity of each peak was different in different spectrum. Second, after samples were radiated by laser, fluorescence weakend along with red shift of its band center, and spectral changes of normal and stomach cancer (after operation) cases were different from other samples. It was also observed that spectral changes of atrophic gastritis were very similar with stomach cancer (such as the red shift of fluorescence peak is more than 12 nm) after radiated by laser, however, there are still some distinctions that can be used to differentiate them from each other. At last, a notable difference is that the relative intensity of peak C excited by 488.0 nm is higher than excited by 514.5 nm in spectrum of stomach cancer, whereas lower in other cases.

Citation Download Citation

Xiaozhou Li, Huiqiang Jin, and Yuepeng Wang "Optical spectroscopy diagnosis for serum of normal and digestive canal cancer", Proc. SPIE 4948, 25th International Congress on High-Speed Photography and Photonics, (1 August 2003); https://doi.org/10.1117/12.516956

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