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12 September 2003 New approaches to total occlusions: the guiding light
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There have been many innovations and technological advancements in balloon angioplasty since its introduction in the late 1970’s, but percutaneous intervention on a totally occluded artery is still a challenge to the vascular interventionalist. Catheter-based intervention that avoids an invasive surgical procedure is a clear and desired advantage for the patient. A total occlusion challenges the interventionalist because the path of the artery can not be seen in the occluded vessel since the flow of the radiopaque contrast media is blocked. Optical coherence reflectometry techniques have been shown to be able to differentiate between artery wall and occlusive materials allowing the lumen of the blocked artery to be seen inside the occlusion. During this past year, a guide wire that uses OCR for forward-looking guidance has received FDA 510(k) clearance and future generation devices that add radio frequency ablation capabilities are in clinical trials. Clinical results show that these new tools are addressing this subset of patients with percutaneous interventions with safety and effectiveness.
© (2003) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
John M. Neet, P. H. Wong, and J. J. R. M. Bonnier "New approaches to total occlusions: the guiding light", Proc. SPIE 4949, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XIII, (12 September 2003);

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