Clinical evaluation of a near-infrared tissue spectrometer in peripheral vascular disease

Xuefeng Cheng; Jian-Min Mao; Xiaorong Xu; Mohamed Elmandjra; Robin Bush; Linda Christenson; Bill O'Keefe; John Bry

doi:10.1117/12.476551

29 July 2003 Clinical evaluation of a near-infrared tissue spectrometer in peripheral vascular disease

Xuefeng Cheng, Jian-Min Mao, Xiaorong Xu, Mohamed Elmandjra, Robin Bush, Linda Christenson, Bill O'Keefe, John Bry

Proceedings Volume 4955, Optical Tomography and Spectroscopy of Tissue V; (2003) https://doi.org/10.1117/12.476551
Event: Biomedical Optics, 2003, San Jose, CA, United States

Abstract

We report results of a feasibility clinical evaluation of the near-infrared Photonify Tissue Spectrometer in detection of peripheral vascular disease (PVD). In the evaluation, using a blood pressured cuff, we measure changes in oxygen saturation (S_tO₂) during a temporary occlusion of blood inflow. We use the post-occlusive S_tO₂ recovery rate and the time needed for 80% recovery as parameters to differentiate healthy subjects from subjects with PVD, and obtained high diagnostic accuracy in 19 subjects enrolled in the clinical evaluation. This may suggest that the tissue spectrometer could be useful in diagnosis of PVD.

Citation Download Citation

Xuefeng Cheng, Jian-Min Mao, Xiaorong Xu, Mohamed Elmandjra, Robin Bush, Linda Christenson, Bill O'Keefe, and John Bry "Clinical evaluation of a near-infrared tissue spectrometer in peripheral vascular disease", Proc. SPIE 4955, Optical Tomography and Spectroscopy of Tissue V, (29 July 2003); https://doi.org/10.1117/12.476551

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available