Flat fluidics: a new route toward programmable biochips

Achim Wixforth; Christoph Gauer; Juergen Scriba; Matthias Wassermeier; Roland Kirchner

doi:10.1117/12.478156

17 January 2003 Flat fluidics: a new route toward programmable biochips

Achim Wixforth, Christoph Gauer, Juergen Scriba, Matthias Wassermeier, Roland Kirchner

Proceedings Volume 4982, Microfluidics, BioMEMS, and Medical Microsystems; (2003) https://doi.org/10.1117/12.478156
Event: Micromachining and Microfabrication, 2003, San Jose, CA, United States

Abstract

The miniaturization of chemical and biological processes has made enormous progress driven mainly by genomics and proteomics. Microfluidics is the core technology to realize miniaturized laboratories with feature sizes on a submillimeter scale. Here, we report on a novel microfluidic technology which allows biochips to be programmed so that different biological assays can be performed with only one chip layout. Interdigital transducers integrated on piezoelectric substrates excite surface acoustic waves (SAW) which drive reagents on the surface of the biochip. The reagents can be placed on any desired spot on the chip’s surface, they can be merged, split and brought to reaction. SAW technology can also be used to efficiently agitate small volumes of liquids accelerating diffusion limited reactions considerably.

Citation Download Citation

Achim Wixforth, Christoph Gauer, Juergen Scriba, Matthias Wassermeier, and Roland Kirchner "Flat fluidics: a new route toward programmable biochips", Proc. SPIE 4982, Microfluidics, BioMEMS, and Medical Microsystems, (17 January 2003); https://doi.org/10.1117/12.478156

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available