Finite element modeling of the Circle of Willis from magnetic resonance data

Juan Raul Cebral; Marcelo Castro; Orlando Soto; Rainald Loehner; Peter J. Yim; Noam Alperin

doi:10.1117/12.480317

2 May 2003 Finite element modeling of the Circle of Willis from magnetic resonance data

Juan Raul Cebral, Marcelo Castro, Orlando Soto, Rainald Loehner, Peter J. Yim, Noam Alperin

Proceedings Volume 5031, Medical Imaging 2003: Physiology and Function: Methods, Systems, and Applications; (2003) https://doi.org/10.1117/12.480317
Event: Medical Imaging 2003, 2003, San Diego, California, United States

Abstract

This paper presents a methodology to construct realistic patient-specific computational fluid dynamics models of the circle of Willis (CoW) using magnetic resonance angiography (MRA) data. Anatomical models are reconstructed from MRA images using tubular deformable models along each arterial segment and a surface-merging algorithm. The resulting models are smoothed and used to generate finite element (FE) grids. The incompressible Navier-Stokes equations are solved using a stabilized FE formulation. Physiologic flow conditions are derived from phase-contrast MR velocity measurements. The methodology was tested on image data of a normal volunteer. A pulsatile flow solution was obtained. Measured flow rates were prescribed in the internal carotid arteries, vertebral arteries, middle cerebral arteries and anterior cerebral arteries. Pressure boundary conditions were imposed in the posterior cerebral arteries. Visualizations of the complex flow patterns and wall shear stress distributions were produced. Potential applications of these FE models include: study the role of the communicating arteries during arterial occlusions and after endovsascular interventions, calculate transport of drugs, evaluate accuracy of 1D flow models, and evaluate vascular bed models used to impose boundary conditions when flow data is unavailable or incomplete.

Citation Download Citation

Juan Raul Cebral, Marcelo Castro, Orlando Soto, Rainald Loehner, Peter J. Yim, and Noam Alperin "Finite element modeling of the Circle of Willis from magnetic resonance data", Proc. SPIE 5031, Medical Imaging 2003: Physiology and Function: Methods, Systems, and Applications, (2 May 2003); https://doi.org/10.1117/12.480317

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available