A mammographic mass CAD system incorporating features from shape, fractal, and channelized Hotelling observer measurements: preliminary results

David Mark Catarious Jr.; Alan H. Baydush; Craig K. Abbey; Carey E. Floyd Jr.

doi:10.1117/12.480868

15 May 2003 A mammographic mass CAD system incorporating features from shape, fractal, and channelized Hotelling observer measurements: preliminary results

David Mark Catarious Jr., Alan H. Baydush, Craig K. Abbey, Carey E. Floyd Jr.

Author Affiliations +

Proceedings Volume 5032, Medical Imaging 2003: Image Processing; (2003) https://doi.org/10.1117/12.480868
Event: Medical Imaging 2003, 2003, San Diego, California, United States

Abstract

In this paper, we present preliminary results from a highly sensitive and specific CAD system for mammographic masses. For false positive reduction, the system incorporated features derived from shape, fractal, and channelized Hotelling observer (CHO) measurements. The database for this study consisted of 80 craniocaudal mammograms randomly extracted from USF's digital database for screening mammography. The database contained 49 mass findings (24 malignant, 25 benign). To detect initial mass candidates, a difference of Gaussians (DOG) filter was applied through normalized cross correlation. Suspicious regions were localized in the filtered images via multi-level thresholding. Features extracted from the regions included shape, fractal dimension, and the output from a Laguerre-Gauss (LG) CHO. Influential features were identified via feature selection techniques. The regions were classified with a linear classifier using leave-one-out training/testing. The DOG filter achieved a sensitivity of 88% (23/24 malignant, 20/25 benign). Using the selected features, the false positives per image dropped from ~20 to ~5 with no loss in sensitivity. This preliminary investigation of combining multi-level thresholded DOG-filtered images with shape, fractal, and LG-CHO features shows great promise as a mass detector. Future work will include the addition of more texture and mass-boundary descriptive features as well as further exploration of the LG-CHO.

Citation Download Citation

David Mark Catarious Jr., Alan H. Baydush, Craig K. Abbey, and Carey E. Floyd Jr. "A mammographic mass CAD system incorporating features from shape, fractal, and channelized Hotelling observer measurements: preliminary results", Proc. SPIE 5032, Medical Imaging 2003: Image Processing, (15 May 2003); https://doi.org/10.1117/12.480868

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available