CAD system for lung cancer screening using low-dose single-slice CT images

Mitsuru Kubo; Nobuhiro Yamada; Yoshiki Kawata; Noboru Niki; Kenji Eguchi; Hironobu Ohmatsu; Ryutaro Kakinuma; Masahiro Kaneko; Masahiko Kusumoto; Hiroyuki Nishiyama; Noriyuki Moriyama

doi:10.1117/12.481305

15 May 2003 CAD system for lung cancer screening using low-dose single-slice CT images

Mitsuru Kubo, Nobuhiro Yamada, Yoshiki Kawata, Noboru Niki, Kenji Eguchi, Hironobu Ohmatsu, Ryutaro Kakinuma, Masahiro Kaneko, Masahiko Kusumoto, Hiroyuki Nishiyama, Noriyuki Moriyama

Author Affiliations +

Proceedings Volume 5032, Medical Imaging 2003: Image Processing; (2003) https://doi.org/10.1117/12.481305
Event: Medical Imaging 2003, 2003, San Diego, California, United States

Abstract

We have been developed a computer-aided diagnosis (CAD) system in the lung cancer detection from a low-dose single-slice CT scanner. The objective of this study is to solve three problems of the conventional CAD system; application of image obtained by other CT scanner, diagnostic procedure for the ground glass shadow less than 5 mm in diameters, and diagnostic procedure for nodule in contact with blood vessels. We analyzed characteristics between each CT images, and pattern of blood vessels. The structural analysis procedure using three-dimensional data is the newly added process. The diagnostic rules to detect nodule consist of the four classes, which are divided by size and CT value. We applied two lung cancer databases; 55 nodules of TCT-900S and 67 nodules of Asteion. The present result from the former database achieved a sensitivity of 94.5%, the latter database achieved a sensitivity of 90.0%. Most of false negative cases had two cases which are a nodule overlapped by blood vessels and a nodule on mediastinum.

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Mitsuru Kubo, Nobuhiro Yamada, Yoshiki Kawata, Noboru Niki, Kenji Eguchi, Hironobu Ohmatsu, Ryutaro Kakinuma, Masahiro Kaneko, Masahiko Kusumoto, Hiroyuki Nishiyama, and Noriyuki Moriyama "CAD system for lung cancer screening using low-dose single-slice CT images", Proc. SPIE 5032, Medical Imaging 2003: Image Processing, (15 May 2003); https://doi.org/10.1117/12.481305

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