Near-infrared spectroscopy and polysomnography during all-night sleep in human subjects

Sergio Fantini; Payal Aggarwal; Kathleen Chen; Maria Angela Franceschini; Bruce L. Ehrenberg

doi:10.1117/12.518756

13 October 2003 Near-infrared spectroscopy and polysomnography during all-night sleep in human subjects

Sergio Fantini, Payal Aggarwal, Kathleen Chen, Maria Angela Franceschini, Bruce L. Ehrenberg

Proceedings Volume 5068, Saratov Fall Meeting 2002: Optical Technologies in Biophysics and Medicine IV; (2003) https://doi.org/10.1117/12.518756
Event: Saratov Fall Meeting 2002 Laser Physics and Photonics, Spectroscopy, and Molecular Modeling III; Coherent Optics of Ordered and Random Media III, 2002, Saratov, Russian Federation

Abstract

We have performed cerebral near-infrared spectroscopy (NIRS) and polysomnography (electro-encephalography, electro-oculography, electro-myography, pulse oximetry, and respiratory monitoring) during all-night sleep in five human subjects. Polysomnography data were used for sleep staging, while NIRS data were used to measure the concentration and the oxygen saturation of hemoglobin in the frontal brain region. Immediately after sleep onset we observed a decrease in the cerebral concentration of oxy-hemoglobin ([HbO₂]) and an increase in the concentration of deoxy-hemoglobin ([Hb]), consistent with a decrease in the cerebral blood flow velocity or an increase in cerebral metabolic rate of oxygen. An opposite trend (increase in [HbO₂] and decrease in [Hb]) was usually observed after transition to deep sleep (stages III and IV). During rapid eye movement (REM) sleep, we observed an increase in [HbO₂] and decrease in [Hb], consistent with an increase in the cerebral blood flow that overcompensates the increase in the metabolic rate of oxygen associated with REM sleep.

Citation Download Citation

Sergio Fantini, Payal Aggarwal, Kathleen Chen, Maria Angela Franceschini, and Bruce L. Ehrenberg "Near-infrared spectroscopy and polysomnography during all-night sleep in human subjects", Proc. SPIE 5068, Saratov Fall Meeting 2002: Optical Technologies in Biophysics and Medicine IV, (13 October 2003); https://doi.org/10.1117/12.518756

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