A UV laser source for biological and chemical sensing

Mikael Tiihonen; Valdas Pasiskevicius; Fredrik Laurell; Per Hammarstrom; Mikael Lindgren

doi:10.1117/12.510471

12 January 2004 A UV laser source for biological and chemical sensing

Mikael Tiihonen, Valdas Pasiskevicius, Fredrik Laurell, Per Hammarstrom, Mikael Lindgren

Proceedings Volume 5240, Laser Radar Technology for Remote Sensing; (2004) https://doi.org/10.1117/12.510471
Event: Remote Sensing, 2003, Barcelona, Spain

Abstract

Optical parametric oscillator (OPO) and sum-frequency mixing (SFM) devices are useful tools for constructing ultraviolet (UV) laser sources for fluorescence spectroscopy. Here, a compact UV-laser sources based on frequency conversion of an actively Q-switched Nd:YAG laser is presented. The second harmonic generation from a Nd:YAG laser was utilized as pump radiation for a periodically poled KTiOPO₄ nanosecond optical parametric oscillator. The OPO-signal and the remaining pump were spatially mode-matched for Type I SFM in a β-barium borate (BBO) crystal and UV radiation at 293 nm could be generated. This corresponds to a conversion efficiency of 2% with respect to the 532 nm harmonic radiation. The wavelength region accessible with this UV source is useful for chemical and biological sensing. Excitation of tryptophan at 293 nm for detection of fluorescence emission in ovalbumin and transthyretin was demonstrated.

Citation Download Citation

Mikael Tiihonen, Valdas Pasiskevicius, Fredrik Laurell, Per Hammarstrom, and Mikael Lindgren "A UV laser source for biological and chemical sensing", Proc. SPIE 5240, Laser Radar Technology for Remote Sensing, (12 January 2004); https://doi.org/10.1117/12.510471

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