In vivo laser soldering of incisions in juvenile pig skins using GaAs or CO2 lasers and a temperature control system

David Simhon M.D.; Marissa Halpern M.D.; Tamar Brosh; Tamar Vasilyev; Naam Kariv; Ronit Argaman; Abraham Katzir; Zvi Nevo

doi:10.1117/12.528948

13 July 2004 In vivo laser soldering of incisions in juvenile pig skins using GaAs or CO₂ lasers and a temperature control system

David Simhon M.D., Marissa Halpern M.D., Tamar Brosh, Tamar Vasilyev, Naam Kariv, Ronit Argaman, Abraham Katzir, Zvi Nevo

Author Affiliations +

Proceedings Volume 5312, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XIV; (2004) https://doi.org/10.1117/12.528948
Event: Biomedical Optics 2004, 2004, San Jose, CA, United States

Abstract

Two temperature controlled laser soldering systems were compared, one based on a GaAs laser and the other on a CO₂ laser. Both systems were used for bonding full thickness incisions. Methods: 47% bovine serum albumin (BSA) solder was used in the CO₂ laser soldering experiments. BSA with 1.8 mg/ml Indocyanine Green (ICG) was used for the GaAs soldering experiments. In both cases the solder was applied onto cuts created in juvenile pig skin and an infrared fiberoptic system was used to monitor and control different temperature and time settings. Differences in tensile strength and wound reparative parameters were compared between GaAs laser, CO₂ laser, and Dermabond glued incisions on the seventh day after the operation. Results: The tensile strength of CO₂ laser-soldered and Dermabond glued incisions were found to be higher than that of the GaAs laser-soldered incisions. Histological study showed better and faster wound healing characteristics of the CO₂ laser soldered incisions, as compared to the GaAs laser-soldered and glued incisions. Conclusions: Preliminary results of temperature controlled CO₂ laser soldered incisions suggest a better wound reparative process over the temperature controlled GaAs laser soldered incisions. Laser soldering offers many advantages over gluing techniques.

Citation Download Citation

David Simhon M.D., Marissa Halpern M.D., Tamar Brosh, Tamar Vasilyev, Naam Kariv, Ronit Argaman, Abraham Katzir, and Zvi Nevo "In vivo laser soldering of incisions in juvenile pig skins using GaAs or CO₂ lasers and a temperature control system", Proc. SPIE 5312, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XIV, (13 July 2004); https://doi.org/10.1117/12.528948

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