A polarized light imaging instrument for characterizing skin lesions

Ian M. Stockford; Stephen P. Morgan; John A. Crowe; John G. Walker

doi:10.1117/12.529030

13 July 2004 A polarized light imaging instrument for characterizing skin lesions

Ian M. Stockford, Stephen P. Morgan, John A. Crowe, John G. Walker

Proceedings Volume 5326, Optical Biopsy V; (2004) https://doi.org/10.1117/12.529030
Event: Biomedical Optics 2004, 2004, San Jose, CA, United States

Abstract

An instrument for imaging skin lesions in four different polarization states and at four wavelengths is described. The instrument is based upon a polarization subtraction method that can be used to extract weakly scattered light and remove surface reflections, without the need to resort to matching fluid and glass plates. Monte Carlo simulations of a layered medium are used to demonstrate the sensitivity of the measurements to the underlying medium. Ideally one would like to extract the absorption, scattering and layer thickness of the medium. However, the problem is ill-conditioned and some prior knowledge of the lesion properties will be necessary for successful implementation.

Citation Download Citation

Ian M. Stockford, Stephen P. Morgan, John A. Crowe, and John G. Walker "A polarized light imaging instrument for characterizing skin lesions", Proc. SPIE 5326, Optical Biopsy V, (13 July 2004); https://doi.org/10.1117/12.529030

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