Building and using a statistical 3D motion atlas for analyzing myocardial contraction in MRI

Nicolas F. Rougon; Caroline Petitjean; Francoise J. Preteux

doi:10.1117/12.535609

12 May 2004 Building and using a statistical 3D motion atlas for analyzing myocardial contraction in MRI

Nicolas F. Rougon, Caroline Petitjean, Francoise J. Preteux

Proceedings Volume 5370, Medical Imaging 2004: Image Processing; (2004) https://doi.org/10.1117/12.535609
Event: Medical Imaging 2004, 2004, San Diego, California, United States

Abstract

We address the issue of modeling and quantifying myocardial contraction from 4D MR sequences, and present an unsupervised approach for building and using a statistical 3D motion atlas for the normal heart. This approach relies on a state-of-the-art variational non rigid registration (NRR) technique using generalized information measures, which allows for robust intra-subject motion estimation and inter-subject anatomical alignment. The atlas is built from a collection of jointly acquired tagged and cine MR exams in short- and long-axis views. Subject-specific non parametric motion estimates are first obtained by incremental NRR of tagged images onto the end-diastolic (ED) frame. Individual motion data are then transformed into the coordinate system of a reference subject using subject-to-reference mappings derived by NRR of cine ED images. Finally, principal component analysis of aligned motion data is performed for each cardiac phase, yielding a mean model and a set of eigenfields encoding kinematic ariability. The latter define an organ-dedicated hierarchical motion basis which enables parametric motion measurement from arbitrary tagged MR exams. To this end, the atlas is transformed into subject coordinates by reference-to-subject NRR of ED cine frames. Atlas-based motion estimation is then achieved by parametric NRR of tagged images onto the ED frame, yielding a compact description of myocardial contraction during diastole.

Citation Download Citation

Nicolas F. Rougon, Caroline Petitjean, and Francoise J. Preteux "Building and using a statistical 3D motion atlas for analyzing myocardial contraction in MRI", Proc. SPIE 5370, Medical Imaging 2004: Image Processing, (12 May 2004); https://doi.org/10.1117/12.535609

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