Effect of projective viewpoint in detecting temporal density changes

Jakob Raundahl; Mads Nielsen; Ole Fogh Olsen; Yu Zhao Bagger

doi:10.1117/12.535319

12 May 2004 Effect of projective viewpoint in detecting temporal density changes

Jakob Raundahl, Mads Nielsen, Ole Fogh Olsen, Yu Zhao Bagger

Author Affiliations +

Proceedings Volume 5370, Medical Imaging 2004: Image Processing; (2004) https://doi.org/10.1117/12.535319
Event: Medical Imaging 2004, 2004, San Diego, California, United States

Abstract

An important question in mammographic image analysis is the importance of the projected view of the breast. Can temporal changes in density be detected equally well using either one of the commonly available views Medio-Lateral (ML) and Cranio-Caudal (CC) or a combination of the two? Two sets of mammograms of 50 patients in a double-blind, placebo controlled hormone replacement therapy (HRT) experiment were used. One set of ML and CC view from 1999 and one from 2001. HRT increases density which means that the degree of separation of the populations (one group receiving HRT and the other placebo) can be used as a measure of how much density change information is carried in a particular view or combination of views. Earlier results have shown a high correlation between CC and ML views leading to the conclusion that only one of them is needed for density assessment purposes. A similar high correlation coefficient was observed in this study (0.85), while the correlation between changes was a bit lower (0.71). Using both views to separate the patients receiving hormones from the ones receiving placebo increased the area under corresponding ROC curves from 0.76 ± 0.04 to 0.79 ± 0.04.

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Jakob Raundahl, Mads Nielsen, Ole Fogh Olsen, and Yu Zhao Bagger "Effect of projective viewpoint in detecting temporal density changes", Proc. SPIE 5370, Medical Imaging 2004: Image Processing, (12 May 2004); https://doi.org/10.1117/12.535319

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