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27 July 2004 Polypyrrole actuators as valves for controlled drug delivery
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Abstract
A controlled drug delivery system in which drug release is achieved by actuating an array of polymeric valves on a set of drug reservoirs is introduced. The valves are bilayer structures, with one layer a thin film of evaporated gold and the other electrochemically deposited polypyrrole. The valves are made in the shape of flaps fixed on one side to the valve seats. Drug reservoirs are covered by an array of such valves, and release of the drugs stored in the reservoirs is accomplished by bending the bilayer flaps back with a small applied bias. The fabrication procedures and proof-of-principle drug release experiments for this controlled drug delivery device are described. Energy consumption of this reversible valve design is compared with metal corrosion based valves developed earlier by other and our group.
© (2004) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Chong Wang, Han Xu, ChunLei Wang, Jim Zoval, and Marc Madou "Polypyrrole actuators as valves for controlled drug delivery", Proc. SPIE 5385, Smart Structures and Materials 2004: Electroactive Polymer Actuators and Devices (EAPAD), (27 July 2004); https://doi.org/10.1117/12.540095
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