Artificial muscle valves for responsive drug delivery systems

Chong Wang; Han Xu; ChunLei Wang; Jim V. Zoval; Marc J. Madou

doi:10.1117/12.548756

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16 August 2004 Artificial muscle valves for responsive drug delivery systems

Chong Wang, Han Xu, ChunLei Wang, Jim V. Zoval, Marc J. Madou

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Proceedings Volume 5455, MEMS, MOEMS, and Micromachining; (2004) https://doi.org/10.1117/12.548756
Event: Photonics Europe, 2004, Strasbourg, France

Abstract

A controlled drug delivery system in which drug release is achieved by actuating an array of polymeric valves on a set of drug reservoirs is introduced. The valves are bilayer structures with one layer, a thin film of evaporated gold and the other, electrochemically deposited polypyrrole, which is also called “artificial muscle”. The valves are made in the shape of flaps fixed on one side to the valve seats. Drug reservoirs are covered by an array of such valves. Release of the drugs stored in the reservoirs is accomplished by bending the bilayer flaps back with a small applied bias. The fabrication procedures and proof-of-principle drug release experiments for this controlled drug delivery device are described. Energy consumption of this reversible valve design is compared with metal corrosion based valves developed earlier by other groups and our group.

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Chong Wang, Han Xu, ChunLei Wang, Jim V. Zoval, and Marc J. Madou "Artificial muscle valves for responsive drug delivery systems", Proc. SPIE 5455, MEMS, MOEMS, and Micromachining, (16 August 2004); https://doi.org/10.1117/12.548756

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