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16 August 2004 Artificial muscle valves for responsive drug delivery systems
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Abstract
A controlled drug delivery system in which drug release is achieved by actuating an array of polymeric valves on a set of drug reservoirs is introduced. The valves are bilayer structures with one layer, a thin film of evaporated gold and the other, electrochemically deposited polypyrrole, which is also called “artificial muscle”. The valves are made in the shape of flaps fixed on one side to the valve seats. Drug reservoirs are covered by an array of such valves. Release of the drugs stored in the reservoirs is accomplished by bending the bilayer flaps back with a small applied bias. The fabrication procedures and proof-of-principle drug release experiments for this controlled drug delivery device are described. Energy consumption of this reversible valve design is compared with metal corrosion based valves developed earlier by other groups and our group.
© (2004) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Chong Wang, Han Xu, ChunLei Wang, Jim V. Zoval, and Marc J. Madou "Artificial muscle valves for responsive drug delivery systems", Proc. SPIE 5455, MEMS, MOEMS, and Micromachining, (16 August 2004); https://doi.org/10.1117/12.548756
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